M1 Overview: Chapters 1-3

Module 1: Foundations

Substance Classifications, Models, and Biology

Understanding what is being interpreted, and how those interpretations shape professional practice.

Module 1 Overview

What this module establishes

Module 1 sets up the rest of the course. It covers three ways of understanding substance use: how substances are classified, how addiction has been explained, and how biology shapes risk. The point is not to memorize terms or pick one correct explanation. It is to see what each way of understanding adds and what it leaves out. Classification gives practitioners accurate, shared language for describing substances and patterns of use. Conceptual models show how different explanations of addiction lead to different responses. The biology explains how genetics and brain processes shape risk without deciding the outcome. No one of these is enough on its own.

Chapter 1

From Categories to Care

Establishes accurate, shared language for describing substances and patterns of use, the roles practitioners hold across the professions, and how language and bias shape care.

Sections: Classification of Substances and Population Patterns · Interprofessional Practice in Substance Use Care · Professional Language

Chapter 2

Different Lenses on Addiction

Compares the major conceptual models of addiction, from moral and disease to biopsychosocial, showing how each explanation points toward a different response.

Sections: Moral Model · Sociocultural Model · Psychological Model · Disease Model · Developmental Life-Course Model · Structural Inequity and Political Economy Model · Biopsychosocial Model

Chapter 3

The Biology of Risk, Without Losing the Person

Explains how genetics and brain processes shape risk without determining the outcome, keeping biology as one dimension of the whole person.

Sections: Interpreting Genetic Risk · Understanding the Brain Without Losing the Person


Why this matters

Holding the perspectives together

How we explain substance use shapes how we respond to the people we are describing. A practitioner who relies on a single explanation, whether moral, psychological, or biological, is poorly prepared for the situations real people bring. The work of this module is to hold the three perspectives together so that what follows in the course rests on more than one way of seeing.

What Module 1 prepares practitioners to do

Use accurate, consistent language to describe substances and patterns of use and misuse in professional settings.
Compare the major conceptual models of addiction and recognize what each one emphasizes and leaves out.
Interpret genetic and neurobiological information as part of a larger picture rather than as a complete or deterministic account.
Recognize how the assumptions built into any explanation shape professional judgment, language, and response.

Moving forward

From foundation to context

This module builds a starting point, not a finished understanding. The next module widens the focus from the individual to the social, historical, and systems conditions that shape how substance use develops and how it is treated.


Foundational Resources

Review before you begin

Please review the links below to develop a foundational understanding of substance use disorder and addiction. This material is intended to establish shared context and conceptual grounding that will support your learning as you move through the chapters in this module.

Supplementary Reading

What is Substance Use Disorder (SUD)?

A clear foundation from the Substance Abuse and Mental Health Services Administration for understanding why this topic matters and why approaching it with an informed, updated perspective is essential for anyone working with individuals affected by substance use and misuse.

Read the Article

Supplementary Reading

Understanding Addiction

The National Institute on Drug Abuse provides a standard definition of addiction and information about what happens to the brain during drug use.

Read the Article

Supplementary Viewing

The Science of Addiction and the Brain

Brainbook (2020). A visual overview of how addiction affects brain chemistry and function, providing biological context for the conceptual material covered in this module.

Watch on YouTube

License

Icon for the Creative Commons Attribution-NonCommercial 4.0 International License

Introduction to Substance Use and Misuse Copyright © 2026 by Scott Coble and Carmelita L. Dotson is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.